ICNC Abstracts, ICNC 2018

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Paediatric Gullain Barre syndrome and its variants – observation of clinico-electrophysiological profile in a tertiary care hospital
Sufia Khatun Sumi

Last modified: 2018-09-09


Background: Gullain Barre syndrome (GBS) is an acute, mostly demyelinating polyradiculoneuropathy  with varied severity of  presentation. There is limited data regarding the clinical and electrophysiological profile  in childhood GBS.

Objective: To study the clinical and electrophysiological profile and treatment modalities in variants of paediatric GBS.

Methods: All the  patients of  GBS of <18 years  admitted  in National Institute of Neurosciences and Hospital  from april 2017- March 2018  were evaluated in this observational study. They were  subjected to NCS and CSF study,  classified into variants of GBS, treated with supportive therapy and IVIG , monitored regularly and transferred to ICU if needed.

Result: Among 42 patients of childhood GBS , M : F was 1.9 : 1. Most of them were within 5-10 years of age. Common presenting features were quadriparesis (78%), pain in affected limbs (68%), swallowing difficulty(21%), nasal intonation(12%), cranial nerve involvement(4%) and others. 54% patient had history of antecedent event and all had protein- cytological dissociation. Majority  revealed AMAN variety  (57%)  followed by AIDP (39%) and AMSAN(4%). 4 patients (13%) required intubation, among them 1 needed tracheostomy. 30 patients received immunoglobulin along with supportive therapy and 75% showed signs of recovery before discharged to home.

Conclusion: Most common age group affected in GBS was 5-10 years, among them axonal variety was predominant.  Majority had quadriparesis followed by sensory symptoms during admission and three fourth of them had clinical improvement.


Gullain Barre Syndrome, Nerve conduction study, Cerebrospinal fluid, Acute motor axonal neuropathy, Acute motor sensory axonal neuropathy, Acute inflammatory demyelinating polyneuropathy, Intravenous immunoglobulin

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