ICNC Abstracts, ICNC 2018

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A prospective study on incidence of non-convulsive status epilepticus in children with acute encephalopathy
sruthi thiruveedi, Dr Lokesh Lingappa, Dr Ramesh Konanki, Dr Nikit shah, Dr Anupama yerra, Dr Farhan Shaikh

Last modified: 2018-09-09

Abstract


INCIDENCE OF NON-CONVULSIVE STATUS EPILEPTICUS IN CHILDREN WITH ACUTE ENCEPHALOPATHY (GCS< 12)- A PROSPECTIVE STUDY

INTRODUCTION

Electrographic status epilepticus in coma is not uncommon. Most electrographic seizures have no clinical correlate, hence require EEG monitoring. Scarce data available on NCSE in Indian pediatric population.

METHODOLOGY

We recruited all the eligible children between 6months-16 years with acute onset encephalopathy (GCS< 12) admitted to our PICU. EEG was recorded on day 1and 3 for 1 hour duration; continuous EEG recordings was taken when required.

RESULTS

25/98 children (26%) had NCSE. 22/25 had clinical seizures (88%), 3 had exclusive NCSE. When compared initial and follow up EEG, 22  had NCSE on day 1 and 14 on day 3. 3/14 had new onset  NCSE on day 3.The most common etiology was FIRES-10/25(Febrile infection related epilepsy syndrome). The most common EEG pattern was Generalized spike and wave morphology(16 children) followed by Ictal rhythms in 13, electro decremental response in 9, PLEDS in 6, GPLEDS in 4,focal discharges in 4, multifocal in 2 and BIPLEDs in one child. 5/25 with  NCSE died (20%). All children died of acute medical conditions. 3/5 had prolonged NCSE lasting >24 h but not statistically significant.

CONCLUSION

NCSE was seen in 25/98 children. FIRES was the most common etiology of NCSE with generalized spike and wave morphology as the most common EEG pattern. NCSE had no significant correlation with mortality.


Keywords


Non-convulsive status epilepticus;Electroencephalogram;Acute encephalopathy;Ictal rhythms,Diffuse cerebral dysfunction

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