ICNC Abstracts, ICNC 2018

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Outcome Following Febrile Seizures: A Scottish Population Cohort
Libby CHATTERTON DICKSON, Ailsa McLellan, Paul Leonard, Clodagh Mitchell, Jay Shetty

Last modified: 2018-11-07

Abstract


Febrile Seizures(FS) are common childhood seizures, reported good prognosis with slight increased risk of epilepsy.  The management of FS is variable in different parts of the world. We aimed to study the population based prevalence, immediate and long-term neurological and educational outcome in children following FS from Scottish population cohort.

All children diagnosed with FS between January-2012 and December-2015 at Scottish Tertiary Hospital were included. Demographic, clinical, investigation, treatment and follow up data were extracted to a database. Socioeconomic data were collected using Scottish Index of Multiple deprivation (SIMD).

There were 689 children(M:F 54.3%:45.7%) diagnosed with FS(median duration 3 minutes, Figure1) accounting 0.7% emergency hospital visits(Table 1). Annual prevalence was 390/100,000 and 2.62% children atleast had one FS by fifth birthday. Mean age of first FS (1.9 years) and younger(<1.9 years) children with first FS are more likely to have recurrent convulsions(p<.001; Figure2), receive emergency medication (p<05), suffer from febrile status epilepticus(p<05), be admitted to hospital (p<.001) and receive hospital follow up (p<.001). 36.3% had more than one FS. Children who had complex FS were more likely to develop epilepsy (8.6% vs 2.6(p<.001). Family history of FC in 8.6% and epilepsy in 3.9%, investigations in 9%(EEG, Imaging and genetic test) recorded. Subsequent epilepsy diagnosis was made in 2.6%(Table 2), correlated with recurrent and/or complex FS(p<0.05).

We report a large cohort of FS with good immediate neurological outcome and we will further explore genetic investigations and long term educational outcome to help parents and also clinicians in management.


Keywords


Febrile Seizures; Febrile Convulsions; Epilepsy

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