ICNC Abstracts, ICNC 2018

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Pediatric status epilepticus. Cases admitted during years 2015-2016 at Hospital de niños Dr. O. Alassia de la ciudad de Santa Fe, Argentina.
Francisco Alberto Astorino, Betiana Comas, María Inés Malatini

Last modified: 2018-09-12

Abstract


Introduction: status epilépticus (SE) a neurological emergency which frequently requires intensive care with  high mortality. The International Leage Against Epilepsy (ILAE) established a new definition:  condition resulting from the faillure of mechanism responsible for seizure termination or from the initiation of control mechanisms, which lead to abnormally prolonged seizures. SE can have  long term consecuences such as, neuronal death,  neuronal injury and changes at neuronal networks  depending on seizure type or duration.  Main Objective: to describe  SE epidemiological aspects in children admitted from 01JAN2015 until 31DEC2016 to Dr Alassia Hospital. Secundary Objetives: to stablish etiology-to find trigger causes-to analyze eeg-to check on treatment and protocols.Material and Methods: 65 children admitted al Dr. O. Alassi Hospital with SE, period 01JAN2015-31DEC2016- Observational and analitic study. Demographyc analysis, complementary studies, first and second line treatment acording to Shorvon 2011 protocol.Results: 65 children, 37 male 28 female, ages 2 month old to 11 years old media 2.64. 43 eeg practiced, 13 eeg with paroxismal activity. All had neuroimages: 21 MRI, 45 TCscan, 12 had encephalic lession. Correlation paroxismal eeg activity-lession: 4 children had paroxismal activity value 0.72 (p:< 0,05)  statistically non significative. Etiology: feber 33, sepsis 12, metabolic disturbances 2, vascular 4, other causes 8, non demonstrable etiology 4. Treatment: 63 required first line benzodiazepines treatment, from those 60 required second line phenobartibal treatment.Conclutions: average age was 2,64 years old, feber was  the most frequent etiology. No significtive correlation between neuroimage lession – eeg. paroxismal activity. 93% required second line treatment.



Keywords


status epilepticus; children; etiology

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