ICNC Abstracts, ICNC 2018

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Long-term neurodevelopmental outcomes following Extracorporeal Life Support and the role of neuroimaging in predicting outcomes
Sailaja Golla, Lakshmi Raman, Archana Dhar, Pilar Martin, Mary Ann Morris, Jefferson Tweed, stacey scott, Vinai Modem

Last modified: 2018-09-09


Objective: To evaluate the long-term neurodevelopmental outcomes in neonatal and pediatric patients supported by ECMO and to identify the role of post-ECMO MRI in predicting neuro-developmental outcomes


Method: Twenty-nine patients were evaluated using the Ages and Stages Questionnaire, Third Edition (ASQ-3) screening tool. Thirteen were evaluated during their visit at the neuro-developmental clinic and 16 were interviewed via phone.


Results: In our cohort of 29 patients 34%  had developmental delay with 80% of these being newborn.  67% of patients with developmental delay had moderate to severe MRI abnormalities as compared to only 18% with no developmental deficits (p-value 0.03).


Conclusion: Younger the age at the time of placement on ECMO, higher the chances of impaired neurodevelopmental outcome.  Long-term follow up of patients who have survived ECMO, with standardized neuro-psychological testing and post ECMO imaging, should become the standard of care to improve long-term outcomes.


ECMO, neruodevelopment, MRI

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